In this review, we examine nanophotonic techniques for enhancing and detecting chirality, with a focus on plasmon-enhanced, tip-enhanced, chiral optical cavities, and photothermal approaches. These methods, which are based on light-matter interactions, provide high sensitivity with challenges in identifying their mechanisms. We discuss recent biomedical applications, emphasizing the potential of nanophotonics in enabling cost-effective and rapid diagnosis with improved chiral signal detection. The review highlights the future potential of chiral nanophotonics in biomedical applications.

https://www.nature.com/articles/s44310-024-00045-2

Yang presented an invited talk on our recent research, “Probing Nanoscale Chirality Using Decoupled Optical Force Nanoscopy,” at the MRS Fall meeting in Boston. It was an incredible event! A big thank you to the EL 08 organizers for the invitation and opportunity to share our work.